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Ginkgolide J

CAS No. 107438-79-9

Ginkgolide J( 7-beta-Hydroxyginkgolide A | BN 52024 )

Catalog No. M20162 CAS No. 107438-79-9

Ginkgolide J has neuroprotective activity it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ginkgolide J
  • Note
    Research use only, not for human use.
  • Brief Description
    Ginkgolide J has neuroprotective activity it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.
  • Description
    Ginkgolide J has neuroprotective activity it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.
  • In Vitro
    ——
  • In Vivo
    Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons.
  • Synonyms
    7-beta-Hydroxyginkgolide A | BN 52024
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    107438-79-9
  • Formula Weight
    424.4
  • Molecular Formula
    C20H24O10
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    C[C@@H]1C(=O)O[C@H]2C[C@]34[C@@H]5OC(=O)[C@]3(O[C@@H]3OC(=O)[C@H](O)[C@]43[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O
  • Chemical Name
    7-beta-Hydroxyginkgolide A

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vitolo O Gong B Cao Z et al. Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide J[J]. Neurobiology of Aging 2009 30(2):257-265.
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